Saturdays in. New Mexico has 23 Indian casinos and 4 Indian gaming travel centers located across 10 counties. Sunday - Thursday: 8 AM - 2 AM | Friday & Saturday: Join the fun at Santa Ana Star Casino Hotel, the best casino in New Mexico! Located just north of Albuquerque, NM, we offer Gaming, Bowling, Golf, Dining. Win. Must be 21+. #1 Best Value of 24 Mexico Casino Hotels ; 2. No Smoking Facility. 1. It's a warm, friendly environment with slot machines. The Travel center includes a casino area with 45 slot machines. at Isleta Resort & Casino. With three live entertainment venues, you'll find something around every corner. Learn More. Our New Mexico casino is open 24/7 daily. Upcoming Events. A warm and friendly environment with slot machines at the Main Casino. Excite. Swirls of Cash. #2 Best Value of 24 Mexico. Unwind. Read More! Sky City's Main Casino and the Travel Center's Slot Area is open 24 hours daily. Open 24 hours, 7 days a week! What's happening. The Pyramid Cancun · 4, reviews. Indulge. Sky City Casino is open 24 hours daily. Colorful bingo cards and round bingo balls w/numbers. Seadust Cancun Family Resort · 6, reviews. These casinos and gaming sites are owned by 14 New Mexico. . Experience Vegas at Albuquerque's Sandia Casino! Test your luck at our slots or play poker, roulette & more! High limit & VIP lounge available. DISCOVER NORTHERN NEW MEXICO AT ITS BEST! The casino is open every day.