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The Rosenmund lab studies basic principles of synaptic transmission with a major focus on the process of neurotransmitter release.
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Here, we show that deletion of the α subunit of Gz in mice: (i) impairs platelet aggregation by preventing the inhibition of cAMP formation normally seen at.
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Wolf, O.
These modulators can either enhance or inhibit mGlu functional responses and, together with mGlu knockout mice, have furthered the establishment. Well of Wishes.
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Ac- cording to SAR study of anti-COS assays, selected derivatives bear an isopropyl moiety, as well as DHA lipophilic function. This bidirectional control of synaptic strength.
This dissertation presents a unique approach to AI for drug discovery based on tightly integrating insights from biochemistry and biophysics, driving a more. Altered synaptic plasticity in a mouse model of fragile X.
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Fragile X is the leading inherited cause of mental retardation and autism. Regulation of distinct AMPA receptor phosphorylation.
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Brabet I, Parmentier ML, De Colle C, Bockaert J, Acher F, and Pin JP () Huber KM, Gallagher SM, Warren ST, and Bear MF () Altered synaptic plas-. Bockaert, et al.
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